A recent analysis showed that mortality from intrahepatic cholangiocarcinoma has increased globally while mortality from extrahepatic cholangiocarcinoma has levelled off or decreased.
Paola Bertuccio , PhD, from the University of Milan in Italy, and colleagues wrote that the increase in ICC-related deaths was likely due to better disease classification, whereas the decrease in ECC-related deaths likely followed the increased use of laparoscopic cholecystectomy.
“These two types of cancer have some recognized differences in risk factors and clinical presentation,” the researchers

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