I read the recent article by Kanai et al. [1] published in January 2019 issue of The Journal of Neurological Sciences entitled “Predictive score for oral corticosteroid-induced initial worsening of seropositive generalized myasthenia gravis”. The authors reported that the scoring system based on three clinical characteristics can predict the likelihood of steroid-induced initial worsening in MG. Despite careful analysis of this study, some methodological issues should be taken into account. In this study univariate and multivariate regression models were applied while the results of the univariate model were not reported.

Source link