GEM: Family history, microbiome, permeability can stratify high-risk IBD

LAS VEGAS — Looking at people with at least one first-degree relative with Crohn’s allowed researchers to further stratify risk among an already high-risk group, determining certain characteristics that put a person at a five-times greater risk of developing Crohn’s, according to an expert at Crohn’s & Colitis Congress.
“This stratification of a high-risk group gives us insight into how these parameters figure into the pathogenesis of Crohn’s,” Ken Croitoru, MD, of Mount Sinai, said during his presentation.
Croitoru presented preliminary data from

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