Gastroenterology

New HCV genotype subtypes present in sub-Saharan Africa






Researchers discovered diverse hepatitis C genotype 4 strains and new genotype 7 strains in sub-Saharan African countries with NS3 and NS5A polymorphisms associated with resistance to direct-acting antivirals in other genotypes, according to recently published data.
“While DAAs are cheap to manufacture and generic formulations are being rapidly developed, several barriers may hinder efforts to eradicate the virus,” Chris Davis, MD, from the University of Glasgow Center for Virus Research in Scotland, and colleagues wrote. “A lack of knowledge about strains circulating in

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