Gastroenterology

Humira levels linked to biologic Crohn’s remission




Patients with optimized Humira drug levels were more likely to achieve biologic remission, according to research published in Inflammatory Bowel Diseases.
“It is increasingly recognized that clinical symptom activity indices correlate poorly with the degree of underlying intestinal inflammation,” Nikolas Plevris, MRCP, of the Edinburgh IBD Unit at Western General Hospital in Edinburgh, Scotland, and colleagues wrote. “In the era of treating beyond symptoms, data are emerging that even higher serum drug levels are required to achieve objective end points like mucosal healing.”

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