In the latest sign of anger over the cost of insulin, the Minnesota attorney general on Tuesday filed a lawsuit accusing the three largest manufacturers — Eli Lilly, Sanofi and Novo Nordisk — with deceptively raising prices, the first state to go to court over the issue.

“Insulin is a life-or-death drug for people with diabetes,” said Minnesota Attorney General Lori Swanson in a statement. “Many people can’t afford the price hikes but can’t afford to stop taking the medication either.” As an example, the lawsuit cited the Lantus insulin sold by Sanofi, which cost $99.35 for a 10-milliliter vial in 2010, now costs $269.54.

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