I appreciate Dr. Munakomi’s comments, on our editorial,1 about the importance of public education to increase treatment opportunities for patients with acute ischemic stroke. At the same time, research to enhance diagnostic tests is needed and might help guide the most appropriate and effective treatments. The work by Bustamante et al.2 brings us one step closer to a potential blood biomarker that may, one day, help guide therapeutic decision making in the setting of acute ischemic stroke.

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