Gastroenterology

Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate

The enzyme stearoyl-coenzyme A desaturase 1 (SCD or SCD1) produces mono-unsaturated fatty acids by introducing double bonds into saturated bonds between carbons 9 and 10, with oleic acid as the main product. SCD1 is present in the intestinal epithelium and fatty acids regulate cell proliferation, so we investigated the effects of SCD1-induced production of oleic acid in enterocytes in mice.

Source link




Related posts

P148 ROLE OF IL-33-DEPENDENT INNATE IMMUNE RESPONSES IN COLITIS-ASSOCIATED CANCER

Newsemia

Villous atrophy in the terminal ileum is a specific endoscopic finding correlated with histological evidence and poor prognosis in acute graft-versus-host disease after allo-hematopoietic stem cell transplantation

Newsemia

CME Exam 2: Environmental Risk Factors for Inflammatory Bowel Diseases: An Umbrella Review of Meta-analyses

Newsemia

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy