Neurology

Brain and spinal cord MRI lesions in primary progressive vs. relapsing-remitting multiple sclerosis

Background: Primary progressive (PP) multiple sclerosis (MS) is considered a clinically distinct entity from the spectrum of relapsing-remitting (RR) forms of the disease.Objective: To compare the presence of brain and spinal cord lesions between PP and RR subjects.Methods: We studied people with PPMS [n = 40, 17 (43%) men, age 50.7 ± 7.7 years, disease duration 10.1 ± 7.4 years, Expanded Disability Status Scale (EDSS) score 4.6 ± 2.1] and RRMS [n = 40, 12 (30%) men, age 47.9 ± 4.2, disease duration 13.7 ± 5.9, EDSS 1.7 ± 1.3].

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